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The NAD+ decline is now recognized as a central node connecting multiple hallmarks of aging, including mitochondrial dysfunction, genomic instability, and cellular senescence

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Neuron (2023) 11(10):156476.e6

This abnormal facilitation of motivational learning resulting from alcohol-induced stimulation of dopamine transmission is believed to underlie the neurobiology of alcohol addiction

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By treating the area of pain and tackling the root driver behind it, we aim to provide long-term relief and prevent future recurrences