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Physiology and pharmacology of effects of GLP-1-based therapies on gastric, biliary and intestinal motility

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Furthermore, it assists the defense system of the body

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Hajszan T, Leranth C, Roth RH

Mecanismo de accin de los agonistas duales GLP-1/GIP Los agonistas duales actan sobre los receptores GLP-1 R y GIP R, ambos acoplados a protenas Gs, estimulando la adenilato ciclasa y aumentando los niveles intracelulares de AMP cclico (AMPc) en las clulas beta pancreticas