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10.1016/0735-1097(89)90505-6 19 HanJ.KaufmanR

Our narrative review discussed the CV benefits of GLP-1 RAs in terms of controlling CV risk factors and improving CV outcomes in diabetic and nondiabetic patients regardless of their CV history, and the CV perspectives related to their use in clinical practice

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While the findings did not address any possible changes to the participants mood, researchers found people who took semaglutide were significantly more willing to exert effort by choosing the "hard" task

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Semaglutide works primarily by enhancing glucose-dependent insulin secretion, suppressing glucagon release, slowing gastric emptying, and reducing appetite through central nervous system pathways