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Long-Lasting Results : Treated veins are permanently closed, though new veins may develop over time

10.1016/s0945-053x(98)90012-9 Matrix Biol

Despite the use of rodents and small mammals being commonplace in research, in particular for the development of novel therapeutic agents, caution still needs to be practiced when extrapolating research data to clinical applications

Visible changes: 4 to 6 sessions are usually required for lasting effects

however, additional work is required to establish this mechanism