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3 Transmembrane transport of Mn and systemic regulation In this review, we separate transmembrane transport at the cell-level uptake/efflux across polarized membranes (e.g., enterocytes, hepatocytes, brain endothelium), and systemic regulation at organ-level fluxes that determine how Mn moves among the intestine, liver, blood, and brain

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Three different mechanisms of GST-catalyzed isomerization are known: (i) carbon-carbon double bond shifts, (ii) intramolecular redox reactions and (iii) cis-trans isomerizations 21

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