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ROS can induce the stabilization of HIF-1, which in turn upregulates VEGF expression, promoting the formation of new blood vessels to supply the growing tumor with nutrients and oxygen [115]

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Ruby CL, Adams CA, Knight EJ, Nam HW, Choi DS

UAE Research suggests that senescent cells impair proteasome activity in the heart, leading to the accumulation of damaged proteins and reduced cardiac function

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All ethical regulations relevant to human research participants were followed