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Sleeve gastrectomy activates the GLP-1 pathway in pancreatic cells and promotes GLP-1-expressing cells differentiation in the intestinal tract

At 30 min (for pERK1/2 staining) or 90 min (for c-Fos staining) after injection, mice were transcardially perfused with phosphate buffer including 4% paraformaldehyde and 0.2% picric acid under anesthesia

10.1172/JCI94601 J Clin Invest

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Biomarker profiling in this way raises the prospect of focusing on the pathophysiology of different metabolic subtypes of autism as well as supporting decisions in therapeutic interventions and clinical trial management (85, 86)