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however, it is unlikely to be a sole action of glutamate excitotoxicity (85)

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2020 Jan;111(1):84-92.

A contaminated or improperly preserved diluent undermines even the highest-purity peptide

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Native IGF-1's extremely short free half-life of 12-15 minutes is primarily determined by rapid IGFBP capture (which removes it from the free pool), renal filtration of the small 7.6 kDa protein, and IGF-1R-mediated endocytosis and lysosomal degradation