Patients with longstanding diabetes (over 10 years) or poor prior glycemic control should undergo comprehensive dilated eye examination before starting GLP-1 medications to establish baseline retinal status
The Phase 2 dose-finding trial (N=338), published in the New England Journal of Medicine in 2023 (DOI: 10.1056/NEJMoa2301972), randomized participants with obesity (BMI 30-50) to retatrutide at doses ranging from 0.5mg to 12mg weekly or placebo over 48 weeks
Incapsula incident ID: 562000140159502995-284169098063119283
In addition to medications and labs, the monthly cost of the plan includes unlimited provider visits and ongoing support
Increased Energy Expenditure: Activation of the glucagon receptor encourages the body to break down stored fat and increases the metabolic rate, further supporting weight loss
That said, legal analysts have provided estimates based on the severity of injuries and precedent from similar litigation