In a cohort of nearly 650,000 South Korean middle-aged individuals with T2DM followed for a median of 6.2 years, those with persistent MASLD had a higher risk of heart failure (hazard ratio???1.28, 95 % confidence interval 1.25-1.32), myocardial infarction (hazard ratio 1.15, 95 % confidence interval 1.10-1.20), ischemic stroke (hazard ratio 1.14, 95 % confidence interval 1.09-1.19), and all-cause mortality (hazard ratio 1.11, 95 % confidence interval 1.09-1.14) than those who never had MASLD (Han et al., 2025[28])
S2CID 7282489
Frequently Asked Questions Is tirzepatide just a stronger version of semaglutide
In current clinical trials, retatrutide side effects have been mild to moderate and most often included: Nausea Diarrhea Vomiting Constipation As noted above, in many of these randomized trials there is a chance that you will be receiving a placebo, so no active drug at all
The medication was effective but required reconstitution before each injection, which patients found inconvenient
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