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Pevec et al., 2010) and worsening, as well as immunosuppression (Sikiric et al., 2003)

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5,61 As an example, orally administered GSH ethyl ester is able to significantly raise GSH concentrations in the liver, kidney, spleen, pancreas, heart, and lung of the mouse, and in human red blood cells, skin fibroblasts, and several lymphoid cell lines

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Their main disadvantages, however, are their high cost, long lifespan, and the need for specialized large-animal facilities