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At the metabolic interface, oxidative stress impairs the Nrf2 antioxidant defense system and compromises mitochondrial membrane integrity [113, 114], while emerging non-apoptotic cell death pathwayssuch as ferroptosis (GPX4/ACSL4) and necroptosis (RIPK1/3MLKL)drive follicular demise in toxin-exposed or inflamed ovaries [79, 115]

BMC Complementary and Alternative Medicine, 16 , 110

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Portland residents who have tried calorie counting, gym memberships, and online programs without lasting results regularly make the short drive to our South Portland clinic for a different approach

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