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Organelle-Specific activity : Ideal for studies observing the long-term impact on cellular models and mitochondrial function variables

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The dehydrogenase form not only preferentially uses NAD+ as an electron acceptor but also is able to donate electrons to molecular oxygen

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5 Conclusions and outlook Conventional HDACi is associated with drug resistance, toxicity, and limited efficacy in clinical applications, making the development of novel HDACi an urgent issue

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