Senescent cells normally accumulate as people age
2 In this study, we evaluated the ability of the BioJet device to deliver a small-peptide therapeutic via needleless injection into the submucosal space of the small intestine in a swine model by measuring systemic exposure to semaglutide after activation of the device
Acknowledgements This work was supported by the National Natural Science Foundation of China (82073313 to D.L.), the joint project of the State Administration of Traditional Chinese Medicine and Health Commission of Shandong Province (GZY-KJS-SD-2023-094), the Traditional Chinese Medicine Special Project of Binzhou Medical University Affiliated Traditional Chinese Medicine Hospital (2023ZYZX02) and the 2023 Qilu Biancang Traditional Chinese Medicine Talent Cultivation Project (to D.L.)
This article compares the two as research compounds: what each one is, the mechanisms each is investigated for, how their preclinical research profiles differ, and why they are sometimes examined together
CagriSema achieved 22.7% at 68 weeks while tirzepatide achieved 22.5% at 72 weeks
10.1186/s40780-017-0083-x 88 SchmidtR