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The aim of this study was to overcome this limitation and develop, optimise and validate a reverse-phase high performance liquid chromatographic (HPLC) assay of GSH and GSSG for the determination of oxidant status in cardiac and chronic kidney diseases

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Furthermore, the concomitant rate of auto-oxidation of doxorubicin within the cell is assumed to be equal to that of the OCR experimental data used to parameterise the model

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Patients on testosterone replacement therapy show variable insulin sensitivity changes