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They are discussed for overlapping reasons, but they come from different biological concepts, are studied through different mechanisms, and raise different safety and regulatory questions

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Higher levels of Vitamin B12 protect against brain changes that happen with aging and less likely to develop dementia and Alzheimers disease

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It may also help modulate growth factors in your body that are involved in tissue repair

GI events (nausea, vomiting, diarrhea) were the dominant safety signal and occurred at rates higher than reported for Phase 2 retatrutide and higher than for comparable dual or mono-agonist trials