The Tet-on-induced TH overexpression in human midbrain-like organoids derived from the induced pluripotent stem cells (iPSCs) has also been shown to induce degeneration of dopaminergic neurons [44]
[DOI] [PubMed] [Google Scholar] Zanassi P, Paolillo M, Montecucco A, Avvedimento EV, Schinelli S (1999) Pharmacological and molecular evidence for dopamine D(1) receptor expression by striatal astrocytes in culture
For hair regrowth specifically, protocols typically employ subcutaneous administration with careful attention to dosing and timing
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Front Cell Neurosci 12:192
Tawarayama, H