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In a novel finding, the in silico analysis revealed a potentially tolerogenic sequence in TPT, which correlated with lower-than-expected de novo immune responses to TPT in vitro

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Strains such as Firmicutes and Proteobacteria, often associated with poor human health, have been shown to produce TMAO

Actin-sorting nexin 27 (SNX27)-retromer complex mediates rapid parathyroid hormone receptor recycling

Clinical trials showed that approximately 4-6% of participants discontinued Zepbound specifically due to gastrointestinal adverse effects