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In the treatment of obesity, prolonged use of semaglutide may result in tolerance and subsequent weight regain following discontinuation [125]
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The typical progression follows a four-week cycle: you maintain each dose level for approximately 28 days before advancing
Long-Term Safety While GLP-1 medications have shown promising results, long-term safety data is still being collected
They regulate blood sugar and appetite by mimicking the action of the naturally occurring gut hormone GLP-1, a modulator of insulin secretion, glucagon, stomach emptying, and satiety signalling