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"Two concentrations of topical tretinoin (retinoic acid) cause similar improvement of photoaging but different degrees of irritation: a double-blind, vehicle-controlled comparison of 0.1% and 0.025% tretinoin creams." Archives of dermatology 131.9 (1995): 1037-1044

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Proc Natl Acad Sci U S A (2006) 103(19):731520.10.1073/pnas.0510033103 208 Barton-DavisERShoturmaDIMusaroARosenthalNSweeneyHL