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13a, Supplementary Table 9), suggesting that the distinct rotamer orientation of H296 ECL2 in Cagri-bound CTR (to accommodate the Glu linker) and/or the observed more open ECL3 conformation induced by the lipidated peptide may facilitate or stabilize an active CTR conformation (Supplementary Fig

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Sudo K, Taketa T, Correa AM, Campagna MC, Wadhwa R, Blum MA, Komaki R, Lee JH, Bhutani MS, Weston B, Skinner HD, Maru DM, Rice DC, Swisher SG , Hofstetter WL, Ajani JA

Archives of Environmental & Occupational Health , vol

[ 3 H] GSSG uptake assay in immunopurified ER SLC33A1 knockout HEK293T or Slc33a1 knockout KPK cells expressing EMC3-mScarlet-3xHA (ER-tag) complemented with a vector control or SLC33A1 cDNA were treated with 1 mM BSO for 48 hours prior for ER isolation

Most dyes are labeled FD&C