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Baseline estimated renal function was normal (eGFR 90 mL/min/1.73 m2) in 65.9%, mildly impaired (eGFR 60 to 90 mL/min/1.73 m2) in 28.5% and moderately impaired (eGFR 30 to 60 mL/min/1.73 m2) in 5.4% of the patients

Rare risks include phlebitis (vein irritation) or a temporary electrolyte shift if high-dose protocols are administered without prior lab work

Both medications serve distinctly different therapeutic purposes and act through entirely separate physiological mechanisms

Degraded material is described as having an uncertain safety profile

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