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PlexusDx Precision Peptide Genetic Test examines variants in GLP1R (rs6923761), GIPR (rs1800437), FTO (rs9939609), and MC4R (rs17782313), among 49 peptides across 14 biological pathways

Insulin stimulates leptin production and secretion in adipocytes [250]

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In parallel, the SURMOUNT trials, which focused on individuals with obesity with or without diabetes, revealed substantial and sustained weight loss that exceeded outcomes typically achieved with existing pharmacologic options