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MOTS-C is on the USADA and WADA prohibited substances list

Athanason AC, Nadav T, Cates-Gatto C, Roberts AJ, Roberto M, Varodayan FP (2023) Chronic ethanol alters adrenergic receptor gene expression and produces cognitive deficits in male mice

Nat Rev Drug Discov 20:689709

However, some people find its aftertaste slightly bitter

Scientific African 22:e01407 Bhattacharjee N, Borah A (2016) Oxidative stress and mitochondrial dysfunction are the underlying events of dopaminergic neurodegeneration in homocysteine rat model of Parkinsons disease