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Concomitantly, GLP-1RAs suppress the expression of lipogenic transcription factors and enzymes, including sterol regulatory element-binding protein 1c (SREBP-1c) and fatty acid synthase (FAS), resulting in reduced de novo lipogenesis

1 Introduction Inflammatory diseases have emerged as a significant global public health concern, encompassing inflammatory bowel disease (IBD), rheumatoid arthritis (RA), metabolic inflammatory disorders, neuroinflammatory conditions, respiratory inflammatory diseases, etc

Standard L-carnitine does not cross it efficiently