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Sangle GV, Chowdhury SK, Xie X, Stelmack GL, Halayko AJ, Shen GX

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The diagnosis of MAFLD is based on the presence of hepatic steatosis (detected by serum biomarker scores, imaging techniques, or liver biopsy) along with any of the following three metabolic conditions: overweight/obesity, T2D, or evidence of metabolic dysregulation (defined by at least two factors among increased waist circumference, hypertension, hypertriglyceridemia, low serum HDL-cholesterol levels and impaired fasting glucose)