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In addition, crizotinib potently inhibited HGF-stimulated endothelial cell survival or invasion and serum-stimulated tubulogenesis in vitro, suggesting that this agent also exhibits antiangiogenic properties [71, 72]

Serotonin is produced in the gut in large amounts for gut motility, and it sends signals to the brain, which affects mood and behavior

Additionally, gut microbiota regulate tryptophan metabolism to produce indole derivatives and modulate the hosts KP pathway, playing a crucial role in immune homeostasis, neural signaling, and energy metabolism balance

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Capsaicin receptor VR1 and ATP-gated ion channel P2X3 in human urinary bladder