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Dosing Calculations: 250 IU = 10 units (0.10 mL) 500 IU = 20 units (0.20 mL) 1,000 IU = 40 units (0.40 mL) HighDose Protocol (for PostCycle Recovery or Severe Suppression) Frequency: Inject 3 times weekly subcutaneously

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However, all patients with a history of depression were excluded from these studies, and none of them reported the results of psychiatric outcomes

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The evidence is limited by small cohorts, heterogeneous study designs, and variable microbiome methodologies