Epigenetic regulation of genes encoding drug-metabolising enzymes The considerable interindividual variability in CYP450 enzyme expression impacts clinical pharmacotherapy
De Marinis YZ, Salehi A, Ward CE, Zhang Q, Abdulkader F, Bengtsson M, Braha O, Braun M, Ramracheya R, Amisten S, Habib AM, Moritoh Y, Zang E, Reimann F, Rosengren AH, Shibasaki T, Gribble F, Renstrm E, Seino S, Eliasson L, Rorsman P: GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosis
10.1093/eurheartj/ehz119 [DOI] [PMC free article] [PubMed] [Google Scholar] 405.Sezai, A
The American Diabetes Association (ADA) Standards of Care emphasize individualized selection based on patient preference, dosing frequency tolerance, insurance coverage, and clinical goals
Calcium activation of cortical neurons by continuous electrical stimulation: frequency dependence, temporal fidelity, and activation density
Although immune cells, such as CD8+ T cells, can recognize mutant antigens expressed on cancer cells and keep them in a dormant state 60 , chronic inflammation can reactivate dormant cancer cells via the EMT process and seed them onto new metastatic sites 61
