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The mild ketosis associated with weight loss on semaglutide is generally benign and indicates effective fat metabolism

In diabetic nephropathy, podocyte NOX4derived HO drives podocyte injury and slit-diaphragm defects, thereby promoting albuminuria [345], whereas in diabetic retinopathy PKC-driven and VEGF-driven permeability changes are tightly linked to oxidative stress [346]

Any potential impact on blood sugar is likely secondary to the underlying condition rather than a direct effect of high B12 19

No, glutathione does not lighten hair

These reports are largely anecdotal and relatively rare