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Some people notice mild nausea or reduced appetite within the first few hours of their initial injection, but meaningful therapeutic effects such as sustained appetite reduction and early weight changes typically develop over the first four to eight weeks as the dose is gradually escalated

We also conducted a mediation analysis to estimate potential mediators and showed that the effect of GLP-1RAs on ED risk was partially mediated by T2D, obesity, hypertension and CVD

Rarely, patients report unusual warmth, spreading redness, or pus drainage, which may indicate infection and warrant immediate medical attention

In fact, Dr

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