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Only change your dosage in close partnership with your doctor, and know that theres no guarantee that youll have success with a smaller dose, even after some trial and error

Although previous studies showed a lack of therapeutic benefit for GIP agonists, current studies show that the glucose lowering and weight loss effects of tirzepatide are at least as effective as GLP-1 RAs with a similar adverse effect profile

Look for strains specifically studied for constipation, such as Bifidobacterium lactis and Lactobacillus reuteri

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Here is where the gap between scientific proof and bold claims becomes the most apparent

10.1093/eurjpc/zwaa147 12 BrayJ