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This can construct a particular BPC 157 pathway along with that of serotonin and dopamine, given the dense presence of dopaminergic neurons and dense projections of the serotonergic systems [175]

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All of these factors can contribute to poor production of glutathione (or of the enzymes that help glutathione to do its work), and many also deplete the GSH that the cells produce (by converting it into GSSG)

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