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For example, biomimetic magnetosome, composed of an Fe 3 O 4 magnetic nanocluster with a TGF- inhibitor loaded inside and a PD-1 antibody anchored on the membrane surface, was developed to promote ferroptosis/immunomodulation synergism in cancer (Zhang F

Secondly, elevated cAMP levels activate protein kinase A (PKA), which subsequently mediates the activation of AMP-activated protein kinase (AMPK)

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Obese asthmatics, specifically the late-onset, non-eosinophilic, steroid-resistant asthma phenotype that has been most refractory to biologic therapy, have a distinct disease biology

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