Haematological parameters typically normalise within approximately 8 weeks of appropriate treatment
Researchers investigated three doses, and found that most didnt normalize their MMA until after the 1,000 microgram dose
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Review meds (e.g., metformin, PPIs), medical conditions (GI surgery, malabsorption), and diet with your clinician
According to NICE Clinical Knowledge Summaries, once B12 deficiency is adequately treated and symptoms resolve, routine monitoring of serum B12 levels is generally unnecessary, as clinical response is the primary indicator of treatment effectiveness
If improvement occurs, continue the protocol that is working