As clinical use of GLP-1 receptor agonists continues to expand, understanding how these medications alter the subjective/interoceptive effects of alcohol will be critical for optimizing their utility in AUD
A study published in the New England Journal of Medicine found that the average weight loss with tirzepatide is an astounding 22.5%, which more than any other medication for weight loss, approaching weight loss results of bariatric surgery
Antiemetic medications are rarely prescribed for GLP-1 nausea but can be considered if lifestyle and dose modifications prove insufficient
Discontinuation rates range from 37% to 81% within the first year, driven by cost, side effects, and access barriers, with weight regain thereafter mediated through hormonal dysregulation, CNS maladaptation to reduced GLP-1 signaling, and -cell dysfunction
PlexusDx ships all compounded medications from licensed 503A compounding pharmacies in secure packaging to maintain stability
Marshmallow root is rich in soothing mucilage, creating a gentle coating effect that has traditionally been used to calm the digestive tract