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If these patients have been successful with weight loss and glycemic control of their diabetes, then they may be hesitant to discontinue GLP-1 receptor agonists even if they are suffering from nausea, constipation, or abdominal discomfortwhich are common given the medications possible mechanism of action on slowing GI motility

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Considerations for Oral Administration Avoids needles and injection-site reactions Convenient to take and to travel with Considerations for Injectable Administration Higher bioavailability than most oral routes More consistent blood levels Faster onset of action Not sure which approach is appropriate for you