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In terms of molecular mechanism, we also discussed the role of endogenous (enzymatic, and non-enzymatic) and exogenous antioxidants (vitamins, plant-derived and other small molecules), including ascorbic acids, -carotene, -tocopherol, -lipoic acid, coenzyme Q10, melatonin, and flavonoids (quercetin, luteolin, kaempferol, epicatechin, catechin, daidzein, genistein, and rutin, etc.) in scavenging of ROS

- **Anti-Aging Benefits**: Stimulates collagen production, reduces wrinkles, and rejuvenates the skin from within

In order to identify additional relevant papers, the references cited in the selected articles were also evaluated

Latif-Hernandez et al., 2020)

Clinical trial data do not apply: Eli Lilly's investigational Retatrutide has been studied in human clinical trials, and adverse event data from those trials are published [3]

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