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Strikingly, the absence of Gclc in FoB resulted in secretory properties that recapitulated those of Gclc -sufficient MZB at both the transcriptional and protein levels (Supplementary Fig

Over 42 days, the ethanol group received 20% ethanol in their drinking water, while losartan was administered intraperitoneally at doses of 1 mg/kg and 3 mg/kg to the treatment groups.The results demonstrated that losartan significantly reduced oxidative stress markers, evidenced by decreased levels of malondialdehyde and increased total thiol levels in renal tissues