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according to the FDA label, patients should use a non-oral contraceptive method or a backup method for 4 weeks after initiation and after each dose escalation

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Nearly all PCOS patients prescribed semaglutide or tirzepatide also had obesity or type 2 diabetes, suggesting use remains primarily tied to metabolic indications, though broader interest in PCOS benefits is growing within scientific literature

Anesthesiology 1972;36:37-41