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Potential Emotional Side Effects and What They Mean While most patients tolerate GLP-1 medications well emotionally, some experience temporary mood fluctuations, irritability, or emotional blunting during dose escalation

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Safety Screening and Provider Coordination for Post-Bariatric GLP-1 Use Post-bariatric patients considering GLP-1 therapy must be screened for contraindications specific to bariatric anatomy, including internal hernias, marginal ulceration, and prior complications

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Multiple congenital cardiac defects, including atrial septal defects, ventricular septal defects, and patent ductus arteriosus have been associated with APA (5, 70, 104, 108)