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Single-cell RNA sequencing reveals the molecular features of peripheral blood immune cells in children, adults and centenarians

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S-adenosylmethionine (SAMe): In a large clinical trial of patients with alcoholic cirrhosis on SAMe, those with mild-to-moderate disease were found to have significantly improved survival and significantly reduced progression to liver transplantation in the SAMe group (88%) versus the control group (71%)

doi: 10.1210/jc.2018-01713 51 ZongYDengKChongWP