For the other proposed uses (Crohn's, celiac, tendonitis), the agency found the effectiveness evidence similarly insufficient, and it noted multiple FDA-approved products already exist to treat UC
doi: 10.1016/j.gtc.2016.09.007
The drug goes into your body
ZepBound, launched for obesity in late 2023, quickly added hundreds of millions in sales by mid-2025, its global sales were already in the hundreds of millions as clinics rolled out the new weight-loss injection
He also underlined how tricky it is to run studies around fertility of medicines whose safety in pregnancy is unknown
Manufacturer guidance and lactation studies have not established clear safety profiles for these medications in breastfeeding populations, which means the medications are typically not recommended during nursing without explicit medical supervision