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Your GP can: Assess whether your weight or BMI warrants clinical intervention Refer you to an appropriate NHS weight management service Discuss licensed pharmacological options if clinically indicated Advise on the risks of using topiramate outside its licensed indications In summary, topiramate is not a weight loss pill

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The economic burden is significant but the personal burden is greater

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The MTHFR gene variation may also be associated with lower levels of methionine, one of the amino acids needed for the bodys own synthesis of carnitine

Tesfu stresses, adding, "A second clue is a significant decline in one's overall energy levels resulting from a failure to consume enough calories to maintain daily needs