If the maximum dose of the initial GLP1RA is being used, then, in the our clinical experience, initiating at a higher dose could be considered
Several non-inflammatory conditions can mimic or worsen AS pain, including: Degenerative or Structural Issues Degenerative arthritis Joint instability These conditions wont improve with traditional AS medications they need their own targeted treatment, such as regenerative medicine options like PRP therapy or prolotherapy
Effective at improving glycaemic control with a low intrinsic risk of hypoglycaemia and the potential for weight reduction, this agent class is an important addition to the prescribing armamentarium
However, another 205-patient RCT reported that, although a minority of patients did experience an ALT rise with 4 g paracetamol daily, this rise resolved following further days of dosing [25]
Otherwise, it appears that Brello is making access to GLP-1 medications pretty easy
-What points in the training cycle will it be especially useful