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For example, spending on products such as chips, sweet bakery, sides, and cookies show some of the largest reductions. GLP-1 households also reduce food-away-from-home expenditures, with breakfast spending declining by nearly 4% and dinner spending decreasing by 6%

Semaglutide averages 15% of body weight

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Orforglipron, on the other hand, is a small-molecule GLP-1 receptor agonist that is better absorbed

Phase 2 weight loss (48 weeks): 8.7% at 2 mg maintenance 4 mg Weeks 58 First dose where therapeutic effects become clinically meaningful