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The LEADER and SOUL trials significantly reduced both fatal and non-fatal MI with liraglutide and semaglutide, respectively [14, 21]

Resistance training Resistance training with weights or bodyweight exercises also reduces blood pressure by approximately 4.5 mmHg systolic

After 50, the body naturally loses muscle mass at a rate of 1-2% per year (sarcopenia), and adding semaglutide-driven calorie restriction on top of age-related muscle loss can be devastating

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