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Structural basis of Integrator-dependent RNA polymerase II termination

showed that markers of an impaired barrier function associated with bacterial translocation as LPS and LBP are increased in the serum of CD patients with active and inactive disease whereas they are only increased in UC patients with active disease

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S.HerremaH.DavidsM.KramerM

Mechanisms and functions of lysosome positioning

Multiple epigenetic clocks were evaluated: first-generation (Horvath, Hannum), second-generation (PhenoAge, GrimAge, including principal-component GrimAge (PCGrimAge), a mortality-linked estimator), the third-generation DunedinPACE, which indexes the pace of aging, and OMICmAge (multi-omic methylation age)