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Endogenous synthesis occurs within the mitochondria, where ALA is enzymatically derived from octanoic acid

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A popular approach is to use peptides for 5 days on, followed by 2 days off, or to alternate months to give your receptors a break

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A Phase 2 study published in The New England Journal of Medicine (Jastreboff et al., 2023) reported substantial weight reduction in participants with obesity