Bile acid sequestrants and cholesterol metabolism
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Accumulated ROS cause oxidative damage to lipids, DNA, and proteins, creating a pro-degenerative cellular environment (Chang and Chen, 2020
The pre-treatment of primary hepatic cells with SAG followed by exposure to CCl4 protected cells against the cytotoxicity, indicating that the extracts counteracted the toxicity of products generated by the metabolism of CCl4
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"Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application"
